Radial
Keratotomy (RK)
Photorefractive Keratectomy (PRK)
NOTICE: As of March 1995, Excimer laser PRK
treatment for myoptic vision correction had not received final FDA
approval. This laser is classified as an investigational device.
The purpose of this laser series is to
educate the General Public on one of today's most promising Ophthalmic
laser procedure.
The information and images on these web
pages were first presented in 1985. The first functional Excimer laser
system was exhibited during the American Academy of Ophthalmology
Conference in Dallas, Texas in 1987.
This material originates from the early
research performed by numerous physicians and physicists in the U.S. and
Europe. At the time, the RK (Radial Keratotomy) had already been
proven a viable treatment for mioptic vision correction.
This
first image is a histological photo of a corneal specimen that had
been irradiated with an Excimer laser emitting at a wavelength of
193nm. This specimen, as viewed through an electron microscope,
reveals a very well defined incision with a striking absence of any
thermal damage. This process is known as Laser
Photoablation. By controlling the pulse rate and exposure
time, the depth of penetration can be predicted very precisely. It
was calculated that 1 joule/cm² ablates corneal tissue to a depth
of 1 µm. {1}
Just
two months after the initial laser irradiation, this histological
image reveals a fillet or "plug" of Epithelium cells that
has filled in the cavity that was created by the photoablation
interaction. Due to the cornea's amazing regenerative properties, new
stroma can be appreciated just below the Epithelium
"plug". This is a remarkable manifestation of the cornea's
"wound healing" ability. [This specimen was stained with
uranyl acetate and lead citrate prior to examination by a
transmission electron microscope]
This
Excimer laser induced Radial Keratotomy was a performed on a
human eye. The laser energy was delivered to the cornea through an eight
incision corneal mask held in place by a slight suction. There are
number of such mask for RK, Astigmatism, Penetrating Keratoplasty,
etc. The slits are clearly seen using the "red reflect"
effect (photographer's red eye effect) for contrast. An Ophthalmic
Operating Microscope (Zeiss OPMI-1) with a 35mm camera attachment
was used to capture this event. [The top of the head is at the six
o'clock position]
This
is the same eye just one week post-op. As you can see, the incisions
are barely noticeable and the aesthetic appearance is very
favorable. The arrows point to the original incision sites. This
laser RK produced a change of about +2 diopters with an initial
penetration depth of 300 microns (about 60% into the central corneal
thickness). The total central corneal thickness of the typical
human eye is about 600 microns. [The bright spot at the two
o'clock position is a reflection off the microscope's halogen illumination
source]
Specific information on the actual
procedure can be viewed at:
The
American Academy of Ophthalmology
TLC
The Laser Center
Footnotes:
- Trokel SL, Srinivasan R, Baren B.
Excimer laser surgery of the cornea. American Journal of
Ophthalmology 1983; 96:710-5.
|